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If I set the size of the orthographic camera to the screen's width, all sprites are pixel perfect - however I am wondering how to put the camera into an isometric 30° angle in relation to the 3D model room + 2D sprites - aswell as what setting to billboard the sprites, and if the camera should be a very long distance away to avoid clipping. Don't worry, the answer doesn't have to pertain to you!
Thank you for the second thing. I set it in project settings but it didn't update the sprite I placed, so that helps alot, chummy!!